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Localized multisystem inflammatory syndrome in children (mis-c), faster recovery outcome: a case report

Abstract

Backgrounds: MIS-C cases emerged approximately 4–5 weeks on average after the peak prevalence of COVID-19. The symptoms could be asymptomatic or mildly symptomatic with fever and cough. It was unknown if these infants’ exhibited symptoms of Kawasaki disease (KD) or toxic shock syndrome (TSS), or whether they represented a condition associated with the continuing COVID-19 epidemic.

Objective: To describe clinical outcome and examination results of localized multisystem inflammatory syndrome in children.

Case presentation: A 23-month-old boy was brought to the pediatric allergy immunology clinic as a referral from a pediatrician with complaints of lump on right preauricular region, which was redden and painful, feels warm, and difficulty opening mouth. There were also multiple small nodules in peri anal area. There was fever for 1 week before admitted, accompanied by a runny nose with clear secretions with no cough. Fever already resolved at presentation. Tonsils are enlarged to T3/T4 without hyperemic nor injection. The presence of fever, conjunctivitis and cracked lips mimicking Kawasaki disease, but electrocardiography and echocardiography were normal. The MISC panel was shown support for MISC, wherein CBC showed presence of lymphopenia, anemia, neutrophilia, and thrombocytosis. Other panel MISC like the erythrocytes sedimentation   rate, quantitative CRP, D-dimer, and quantitative IgG SARS-COV-2 antibodies it was reported to be increased. The patient was treated with intravenous high doses methylprednisolone pulse 10 mg/kg, then tapered off before stopped. The lump was disappeared after the second dose of HDMP, and patient was discharged after 7 days of admission.

Conclusion: We reported a localized Multisystem Inflammatory Syndrome (MIS-C) treated with high dose methylprednisolone resulting in fast recovery.

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How to Cite

Wintari, P. N., Wati, K. D. K., & Utama, I. M. G. D. L. U. (2024). Localized multisystem inflammatory syndrome in children (mis-c), faster recovery outcome: a case report. Intisari Sains Medis, 15(1), 513–518. https://doi.org/10.15562/ism.v15i1.1976

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Putu Nandika Wintari
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Ketut Dewi Kumara Wati
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I Made Gede Dwi Lingga Utama Utama
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