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Risk factor of progression of diabetic retinopathy after cataract surgery: a systematic review and meta-analysis


Background: Several researchers have looked into the connection between cataract surgery and the progression of diabetic retinopathy (DR) in various studies. However, the element that places a patient at risk for the advancement of diabetic retinopathy following cataract surgery is still unknown. The primary goal of this meta-analysis is to conduct a comprehensive review of the existing research discussing the factors connected to the progression of diabetic retinopathy after cataract surgery.

Methods: A literature search in scientific literature databases, including Pubmed, ScienceDirect, and Cochrane Library, was conducted. Review Manager 5.4 (Cochrane Collaboration, Oxford, UK) measured and analyzed the risk factor's role in the progression of DR after cataract surgery. A significance value below 0.05 was determined statistically significant. 

Results: This review included 657 people from eight different studies. It discovered a significant impact of various parameters on the evolution of diabetic retinopathy after cataract surgery. Serum HbA1c levels (with a mean difference of 1.16; p<0.00), diabetes duration (with a mean difference of 1.89; p=0.02), age at cataract surgery (with a mean difference of -1.72; p=0.01), and insulin treatment (with an odds ratio of 3.74; p<0.00) all demonstrated significant associations with diabetic retinopathy progression after cataract surgery.

Conclusion: Our meta-analysis found that blood HbA1c level, diabetes duration, age at cataract surgery, and insulin treatment were all significant risk variables for postoperative DR progression.


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How to Cite

Saraswati, P. P. T., Nyoman Yuni Suryani Dharmaputri P, Suryathi, N. M. A. ., & Andayani, A. . (2024). Risk factor of progression of diabetic retinopathy after cataract surgery: a systematic review and meta-analysis. Intisari Sains Medis, 15(1), 414–419.




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Putu Putri Titamia Saraswati
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Nyoman Yuni Suryani Dharmaputri P
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Ni Made Ari Suryathi
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Ari Andayani
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